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Article

JAK2 pathogenic variants in ischemic stroke: low prevalence and pre-screening model.

Journal of neurology - 7 Feb 2026

Zhao Jialu, Ge Siqi, Gao Shujun, Xue Liting, Shi Yanfeng, Lu Chaoxia, Fang Fang, Wang Hui, Zhang Yumei, Zhang Yulin, Guo Cang, Wang Meng, Zhang Yijun, Zheng Manqi, Xu Qin, Wang Anxin, Gu Hongqiu, Zhu Wanlin, Jiang Yong, Li Hao, Meng Xia, Wang Yongjun, Li Wei

Abstract excerpt

OBJECTIVE: Our study aimed to determine the prevalence and clinical phenotypes of JAK2 pathogenic mutation carriers in the CNSR-III ischemic stroke (IS) cohort, and to develop a pre-test genetic screening model for identifying high-risk individuals. METHODS: We performed retrospective characterization of JAK2 pathogenic variants using targeted sequencing data in the CNSR-III cohort. Clinical and laboratory...

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PMID: 41654631
DOI: 10.1007/s00415-026-13658-8

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JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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