Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bilateral lung transplantation for severe lung disease caused by a STING1 mutation: A case report.

Transplant immunology - 1 Apr 2026

Lv Yan, Wang Qi, Wang Ke, Cai Yixin, Wang Meijia, Huang Zhenli, Zhang Ruijie, Wang Junhui, Xu Suqin, Shi Huibo, Zhang Huilan, Zhang Ni

Abstract excerpt

Stimulator of interferon genes (STING)-associated vasculopathy with onset in infancy (SAVI) is an autoinflammatory syndrome caused by mutations in the stimulator of interferon response cGAMP interactor 1 (STING1) gene, leading to lung and vascular injury. Most patients with SAVI develop disease in childhood or adolescence and rapidly progress to respiratory involvement, primarily interstitial pneumonia (IP)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lung Diseases, Interstitial
Share to Lung Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Mutation

Source

Identifiers

PMID: 41651191
DOI: 10.1016/j.trim.2026.102359

Genes

STING1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bilateral lung transplantation for severe lung disease caused by a STING1 mutation: A case report.PMID 41651191Read ↗

[STING-associated vasculopathy with onset in infancy: a case report].Semantic proximity Read ↗

Interstitial lung disease and the STING pathway.Semantic proximity Read ↗

Severe interstitial lung disease as the first manifestation of a STING1 variant in a familial case.Semantic proximity Read ↗

Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients.Semantic proximity Read ↗

Severe Pulmonary Fibrosis as the First Manifestation of Interferonopathy (TMEM173 Mutation).Semantic proximity Read ↗

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in InfancySemantic proximity Read ↗

STING–STAT3–SOX18 Axis Drives EndMT and Epigenetic Reprogramming in SAVI Lung FibrosisSemantic proximity Read ↗

STING-Associated Vasculopathy with Onset in Infancy in Three Children with New Clinical Aspect and Unsatisfactory Therapeutic Responses to Tofacitinib.Semantic proximity Read ↗

Cell dichotomous role of STING in pulmonary hypertensionSemantic proximity Read ↗

Phenotypic spectrum in recessive STING-associated vasculopathy with onset in infancy: Four novel cases and analysis of previously reported cases.Semantic proximity Read ↗

A rare manifestation of STING-associated vasculopathy with onset in infancy: a case report.Semantic proximity Read ↗

Stimulator of Interferon Genes-associated Vasculopathy with an Onset in Infancy Diagnosed after the Development of Atypical Pulmonary Lesions During Treatment as Juvenile Idiopathic Arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.