Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variant interpretation in tumours in the French national ring trials Gen&Tiss - main criteria of improvement.

Virchows Archiv : an international journal of pathology - 1 Mar 2026

Kalimulaeva Medina, Van Langenhoven Leen, Leroy Karen, Soubeyran Isabelle, Harle Alexandre, Lamy Aude, Lacroix Ludovic, Fetique Dominique, Gaire Anne, Bellocq Jean-Pierre, Dequeker Els, Rouleau Etienne

Abstract excerpt

Cancer progression is driven by the accumulation of genetic variants, with technological advances increasing their detection. Precise variant interpretation is essential for clinical decision-making, necessitating robust quality assurance programmes. However, variability in interpretation can influence clinical outcomes. This study examines factors contributing to interpretation variability across French...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to France
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Genetic Variation

Share to Neoplasms

Source

Identifiers

PMID: 41649514
DOI: 10.1007/s00428-025-04391-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variant interpretation in tumours in the French national ring trials Gen&Tiss - main criteria of improvement.PMID 41649514Read ↗

Cancer Variant Interpretation Group UK (CanVIG-UK): updates on an exemplar national subspecialty multidisciplinary networkSemantic proximity Read ↗

Oncogenicity Variant Interpreter (OncoVI): oncogenicity guidelines implementation to support somatic variants interpretation in precision oncologySemantic proximity Read ↗

Cancer Variant Interpretation Group UK (CanVIG-UK): an exemplar national subspecialty multidisciplinary network.Semantic proximity Read ↗

Implementation of circulating tumour DNA multi-target mutation testing in plasma: a perspective from an external quality assessment providers' survey.Semantic proximity Read ↗

[Variant interpretation in molecular pathology and oncology : An introduction].Semantic proximity Read ↗

Insights on improving accessibility and usability of functional data to unlock its potential for variant interpretationSemantic proximity Read ↗

Reporting of somatic variants in clinical cancer care: recommendations of the Swiss Society of Molecular Pathology.Semantic proximity Read ↗

Evaluation of <i>in silico</i> algorithms for use with ACMG/AMP clinical variant interpretation guidelinesSemantic proximity Read ↗

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology.Semantic proximity Read ↗

An Educational Assessment of Evidence Used for Variant Classification: A Report of the Association for Molecular Pathology.Semantic proximity Read ↗

Variant Interpretation for Cancer (VIC): a computational tool for assessing clinical impacts of somatic variantsSemantic proximity Read ↗

Multi-Institutional Evaluation of Interrater Agreement of Variant Classification Based on the 2017 Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.