Early-onset hypertension associated with a CACNA1H variant of uncertain significance: a case report and literature review.

Abstract excerpt

BACKGROUND: The prevalence of early-onset hypertension is rising annually and is accompanied by progressive target organ damage, contributing to a higher risk of cardiovascular mortality. In patients with early-onset hypertension characterized by refractory hypertension, elevated plasma aldosterone levels, and a family history of hypertension, monogenic hereditary hypertension, such as familial...

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