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Article

Many faces of non‑deletional α‑thalassaemia variants in neonate and early childhood.

Annals of hematology - 4 Feb 2026

Komvilaisak Patcharee, Laoaroon Napat, Paopongsawan Pongsatorn, Jirapradittha Junya, Kiatchoosakun Pakaphan, Suwannaying Kunanya, Komwilaisak Ratana, Lerttham Worrawalan

Abstract excerpt

Non-deletional α-thalassemia variants, particularly hemoglobin Constant Spring (Hb CS) and hemoglobin Pakse, are prevalent in northeastern Thailand and neighboring regions. Homozygous Hb CS and compound heterozygous Hb CS/Hb Pakse can present with a wide clinical spectrum. In this study, 49 patients with these α-globin variants-with or without co-inheritance of beta-thalassemia-were evaluated. Genotypes included...

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Identifiers

PMID: 41634277
DOI: 10.1007/s00277-026-06856-x
PMCID: PMC12868060

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CS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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