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Article

Primary Cutaneous Peripheral T-Cell Lymphoma With TFH Phenotype With Divergent Clonal B- and Plasma-Cell Populations and DNMT3A Mutation.

Journal of cutaneous pathology - 1 May 2026

Chaudhary Sahil, Fan Jinbo, Obiorah Ifeyinwa E

Abstract excerpt

Primary cutaneous peripheral T-cell lymphoma with T-follicular helper phenotype (pcTFH-PTCL) is rare, and concurrent clonal B-lineage proliferations are uncommon. This lymphoma subtype presents unique diagnostic challenges due to its rarity and potential for misdiagnosis. We present a case of pcTFH-PTCL in an 88-year-old man with pruritic nodules on the shoulders, later developing multifocal cutaneous lesions...

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Topics

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA (Cytosine-5-)-Methyltransferases

Share to DNA Methyltransferase 3A

Share to Lymphoma, T-Cell, Cutaneous

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Source

Identifiers

PMID: 41611211
DOI: 10.1111/cup.70065

Genes

DNMT3A
BCL6
CD4
ICOS
IGH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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