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Heteroresistance in vancomycin-variable Enterococcus faecium ST80 isolate.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2026

Simoni Serena, Di Gregorio Alessandra, Caucci Sara, Brenciani Andrea, Giovanetti Eleonora, Vignaroli Carla

Abstract excerpt

PURPOSE: To investigate the gradual genetic changes occurred in heteroresistant vancomycin-variable (VVE) Enterococcus faecium ST80 isolate - belonging to the vanA ST80 nosocomial clone although recovered from marine environment - contributing to its reversion to a resistant phenotype after exposure to increasing concentrations of vancomycin. METHODS: WGS of the parental strain and three revertants obtained by...

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PMID: 41606382
DOI: 10.1007/s10096-026-05416-5

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