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X- vs. Y-chromosome dosage effects on human cognition: a deep phenotypic comparison of 47,XXY and 47,XYY syndromes.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence - 1 Jul 2026

Larsen Isabella G, Liu Siyuan, Rau Srishti, Schaffer Lukas, Ajumobi Tiffany, Warling Allysa, Whitman Ethan T, Clasen Liv S, Torres Erin N, Mollerstuen Siena, Raznahan Armin

Abstract excerpt

Sex chromosome aneuploidies are associated with a wide range of neurodevelopmental outcomes, and notably, confer risk for cognitive impairments with varying degrees of severity. Yet, to date, few studies have compared multiple cognitive outcomes between different sex chromosome aneuploidy karyotypes, and it remains unclear how cognitive variation is linked to other elements of functioning. Leveraging...

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Identifiers

PMID: 41592873
DOI: 10.1080/09297049.2026.2616523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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