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Article

Analysis of LRP1 gene mutation in developmental dysplasia of the hip: a case series.

BMC medical genomics - 24 Jan 2026

Cheng Tianze, Zhang Weiling, Cheng Hui

Abstract excerpt

Developmental dysplasia of the hip (DDH) is a multifactorial disorder that affects 0.56-3.8% of newborns worldwide. Recent research has identified several candidate genes potentially involved in DDH pathogenesis, with LRP1 investigated as a candidate gene due to its regulatory role in cartilage development. This study presents a genetic analysis of two female DDH patients (17 and 26 years old) diagnosed through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41580695
DOI: 10.1186/s12920-026-02316-7
PMCID: PMC12911242

Genes

LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

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