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Article

Immune Escape-Related Gene NXT1 as a Potential Prognostic and Therapeutic Target in Hepatocellular Carcinoma.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 25 Aug 2025

Guo Jia, Tong Xin, Liu Songtao, Liu Feng, Qu Yachao, Li Ren, Bao Xuli

Abstract excerpt

BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) constitutes approximately 85% of liver cancers. This study aimed to investigate the role of immune escape-related genes (IEGs) in HCC patients and analyze their relationship with prognosis and immunotherapy, thereby providing a reference for further clinical treatment. MATERIALS AND METHODS: Datasets were collected from The Cancer Genome Atlas (TCGA) and Gene...

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Topics

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Share to Biomarkers, Tumor
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 41578763
DOI: 10.5152/tjg.2025.24193
PMCID: PMC12824892

Genes

NXT1
CCK
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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