Article
Furmonertinib in lung adenocarcinoma with EGFR exon 20 insertion mutation: A case report of positive outcome.
Medicine - 23 Jan 2026
Wang Qilin, Zeng Beilei, You Chuanyu, Xu Tian, Chen Xinyu, Yang Xueping, Ye Juncai, Gui Yan
Abstract excerpt
RATIONALE: epidermal growth factor receptor (EGFR) mutations play a pivotal role in non-small cell lung cancer (NSCLC), with the EGFR exon 20 insertion (EGFR20ins) mutation being the third most prevalent alteration in the EGFR gene. Patients harboring this mutation typically exhibit a greater tumor burden and poorer overall prognosis. This mutation is strongly associated with resistance to EGFR-TKIs, presenting...
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