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Article

Mitochondrial heterogeneity drives the evolution of fungicide resistance in Phytophthora sojae, with associated fitness trade-offs.

Science advances - 23 Jan 2026

Yuan Kang, Dai Tan, Gao Xuheng, Shen Jiayi, Yang Jikun, Lu Xingxing, Li Guixiang, He Ya, Fu Yixin, Wang Yan, Miao Jianqiang, Liu Xili

Abstract excerpt

Mitochondrial complex III inhibitors, such as ametoctradin, are crucial for controlling oomycete diseases. However, the increasing severity of fungicide resistance necessitates urgent clarification of its evolutionary mechanisms to optimize disease management and delay resistance development. The DddA-derived cytosine base editors (DdCBEs)-mediated base editing in oomycetes confirmed that the PsCytbS33L mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41576162
DOI: 10.1126/sciadv.adz4601
PMCID: PMC12829574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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