Article
A quorum-sensing molecule from Pseudomonas aeruginosa induces defensive multicellularity in a coinfecting pathogen.
Proceedings of the National Academy of Sciences of the United States of America - 27 Jan 2026
Katharios-Lanwermeyer Stefan, Zarrella Tiffany M, Godsil Marshall, Severin Stefanie, Casiano Alejandro E, Tai Chin-Hsien, Khare Anupama
Abstract excerpt
Microorganisms commonly exist in polymicrobial communities, where they can respond to interspecies secreted molecules by altering behaviors and physiology; however, the underlying mechanisms remain underexplored. Here, we investigated interactions between Stenotrophomonas maltophilia and Pseudomonas aeruginosa, coinfecting opportunistic pathogens found in pneumonia and chronic lung infections, such as in cystic...
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