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Article

Elevated type I interferon signature in patients with chronic granulomatous disease.

Clinical and experimental immunology - 6 Jan 2026

Aggarwal Ridhima, Vignesh Pandiarajan, Dod Aditya, Vinay Keshavamurthy, Sharma Saniya, Singh Surjit, Rawat Amit

Abstract excerpt

Chronic granulomatous disease (CGD) patients develop repeated infections and inflammatory complications. Underlying pathogenesis of hyperinflammation in CGD is not clearly characterized. To assess type-1 interferon signature and measure Siglec-1/CD169 expression on monocytes in patients with CGD. mRNA sequencing of PBMCs in five CGD patients and three controls was analysed for differentially expressed genes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41559882
DOI: 10.1093/cei/uxag003
PMCID: PMC12865451

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CYBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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