Article
Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India.
Frontiers in immunology - 1 Jan 2021
Rawat Amit, Vignesh Pandiarajan, Sudhakar Murugan, Sharma Madhubala, Suri Deepti, Jindal Ankur, Gupta Anju, Shandilya Jitendra Kumar, Loganathan Sathish Kumar, Kaur Gurjit, Chawla Sanchi, Patra Pratap Kumar, Khadwal Alka, Saikia Biman, Minz Ranjana Walker, Aggarwal Vaishali, Taur Prasad, Pandrowala Ambreen, Gowri Vijaya, Desai Mukesh, Kulkarni Manasi, Hule Gauri, Bargir Umair, Kambli Priyanka, Madkaikar Manisha, Bhattad Sagar, Ginigeri Chetan, Kumar Harish, Jayaram Ananthvikas, Munirathnam Deenadayalan, Sivasankaran Meena, Raj Revathi, Uppuluri Ramya, Na Fouzia, George Biju, Lashkari Harsha Prasada, Kalra Manas, Sachdeva Anupam, Seth Shishir, Sabui Tapas, Gupta Aman, van Leeuwen Karin, de Boer Martin, Chan Koon Wing, Imai Kohsuke, Ohara Osamu, Nonoyama Shigeaki, Lau Yu Lung, Singh Surjit
Abstract excerpt
Background: Chronic granulomatous disease (CGD) is an inherited defect in phagocytic respiratory burst that results in severe and life-threatening infections in affected children. Single center studies from India have shown that proportion of autosomal recessive (AR) CGD is more than that reported from the West. Further, affected patients have high mortality rates due to late referrals and difficulties in...
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