Article
Next-Generation Short-Read Sequencing Reveals Impacts on Major Histocompatibility Complex Diversity Resulting From Differences in Captive Rhesus Macaque (Macaca Mulatta) Colony Expansion Strategies.
American journal of primatology - 1 Jan 2026
Kanthaswamy Sreetharan, Wiseman Roger W, Stauss Miranda R, Ertl Max C, Patel Divy K, Smith David G, Martínez Melween I, Maldonado Elizabeth, Sariol Carlos A
Abstract excerpt
The Caribbean Primate Research Center's (CPRC) specific-pathogen-free (SPF) rhesus macaque (Macaca mulatta) colony was established between 1998 and 2002 with 87 founders from Cayo Santiago. Colony expansion continued with the rederivation of animals from their SPF predecessors, while additional animals were still being relocated from Cayo Santiago. The CPRC's major histocompatibility complex (MHC) database,...
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