Genotypic and phenotypic characterization of Pseudomonas aeruginosa PAV112: a virulent clinical strain causing severe pneumonia and lethal sepsis in a murine infection model.

doi:10.1007/s42770-025-01830-7

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Genotypic and phenotypic characterization of Pseudomonas aeruginosa PAV112: a virulent clinical strain causing severe pneumonia and lethal sepsis in a murine infection model.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 16 Jan 2026

Assunção Raissa Guará, Vila Nova Beatriz Gomes, Alves Lully Gabrielly Silva, da Silva Leticia Cely Tavares, Sá Gabrielle Chaves, Dos Santos Silva Lucas, Andrade-Silva Marcos, de Santana Amanda Vitória Sevidanes, Zafred Ivana Fiquene, Soares Sarah Rackel Silva, Nogueira Francisco Jonathas Rodrigues, Bomfim Maria Rosa Quaresma, do Nascimento Johnny Ramos, Carvalho Rafael Cardoso, de Sá Sousa Joicy Cortez, da Costa Marliete Carvalho, Abreu Afonso Gomes

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen frequently associated with hospital-acquired infections, particularly in intensive care units. This study aimed to evaluate the virulence of the clinical strain P. aeruginosa VAP112, isolated from a patient with ventilator-associated pneumonia (VAP), using a murine model of pulmonary infection. Antimicrobial susceptibility testing was performed using the VITEK®...

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PMID: 41543638
DOI: 10.1007/s42770-025-01830-7
PMCID: PMC12811205

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