Genomic analysis elucidates characteristics and possible origins of high-risk antimicrobial resistance genes in Enterococcus faecium from a global perspective

Abstract excerpt

Under the One Health framework, it is crucial to undertake a comprehensive analysis of antimicrobial resistance (AMR) across various countries and regions. High-risk ARGs pose a severe threat to human health, yet systematic research on them is scarce. This study developed a high-risk ARGs database using the existing risk assessment system and explored a genome-based investigation workflow for high-risk ARGs. We...