Article
[Extramedullary blast crisis limited to the lymph nodes in chronic myeloid leukemia with a T/myeloid mixed phenotype].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2025
Maeda Toaki, Hatta Shunsuke, Kanba Keita, Watanabe Tatsuya, Kiba Daichi, Kawajiri Akihisa, Inokura Kyoko, Onodera Koichi, Onishi Yasushi, Fukuhara Noriko, Ichinohasama Ryo, Harigae Hideo
Abstract excerpt
Blast crisis (BC) in chronic myelocytic leukemia (CML) typically presents with increased blasts in the bone marrow, showing either myeloid or B-lymphoid phenotypes. We report a rare case of CML-BC with a T/myeloid mixed phenotype localized to the lymph nodes. An 80-year-old woman presented with right axillary lymphadenopathy. PET-CT revealed multiple enlarged lymph nodes. Axillary node biopsy showed proliferation...
Topics
- Humans
- Female
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Blast Crisis
- Aged, 80 and over
- Lymph Nodes
- Phenotype
- Dasatinib
- Fusion Proteins, bcr-abl