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Genotype-phenotype correlations in breast cancer susceptibility: evaluating MMP-2, TYMS, and eNOS variants in the Jordanian population.

Scientific reports - 8 Jan 2026

Alorjani Mohammed, Al-Eitan Laith, Ali Haneen, Ghabbish Malek

Abstract excerpt

Breast cancer (BC) is a complex, polygenic, and heterogeneous disease influenced by both genetic and environmental factors. Several genetic polymorphisms, including single nucleotide variants (SNVs) and variable number tandem repeats (VNTRs), have been implicated in BC susceptibility and prognosis across diverse populations. This study aimed to assess the association between genetic variants in the MMP-2, TYMS,...

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Identifiers

PMID: 41507280
DOI: 10.1038/s41598-025-34531-0
PMCID: PMC12864866

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TYMS

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