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High-risk human papillomavirus genotype prevalence in Singapore cervical samples: Implications for clinical management.

Annals of the Academy of Medicine, Singapore - 17 Dec 2025

Nandakumar Vivekanathan, Krishnan Satheeskumar, Chang Chia-Pin, Yee Sidney, Ho Sherry Sze Yee

Abstract excerpt

Introduction: Human papillomavirus (HPV) causes over 95% of cervical cancers. The American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines support a risk-based approach using the most informative test, which may include high-risk (HR) or extended genotyping. Most laboratories perform partial genotyping. This study reports findings from the comprehensive genotyping of all 14 HR HPV genotypes in...

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PMID: 41492883
DOI: 10.47102/annals-acadmedsg.2025336

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