The role of human papillomavirus genotyping for detecting high-grade intraepithelial neoplasia or cancer in HPV-positive women with normal cytology: a study from a hospital in northeastern China.

doi:10.1186/s12885-020-06935-w

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Article

The role of human papillomavirus genotyping for detecting high-grade intraepithelial neoplasia or cancer in HPV-positive women with normal cytology: a study from a hospital in northeastern China.

BMC cancer - 19 May 2020

Zhang Jing, Zhang Deyu, Yang Zhuo, Wang Xiaobin, Wang Danbo

Abstract excerpt

BACKGROUND: Human papillomavirus (HPV) testing is more sensitive than cytology for detecting cervical cancer and its precursors. This study aimed to analyze the prevalence of high-risk HPV genotypes and evaluate the role of HPV genotyping triage for detecting high-grade squamous intraepithelial lesions, adenocarcinoma in situ and cervical cancer (HSIL+) in HPV-positive women with normal cytology. METHODS: A...

Topics

Adult
Aged
Alphapapillomavirus
China
Cytodiagnosis
DNA, Viral
Early Detection of Cancer
Female
Follow-Up Studies
Genotype
Hospitals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Middle Aged

Neoplasm Grading

Papillomavirus Infections

Retrospective Studies

Uterine Cervical Neoplasms

Uterine Cervical Dysplasia

Source

Open in PubMed Open full text

Identifiers

PMID: 32429919
DOI: 10.1186/s12885-020-06935-w
PMCID: PMC7236298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32429919-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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