Article
High throughput HPV genotyping by next generation sequencing for detection of 28 HPV types and 13 sexually transmitted infections: A first community-based cervical cancer screening study from India.
Diagnostic microbiology and infectious disease - 1 Apr 2026
Madhavan Yasasve, Muthukumar Vasanthkumar, Ramasubramanian Srinidhi, Ramshankar Vijayalakshmi
Abstract excerpt
BACKGROUND: High-risk human papillomavirus (HR-HPV) infection is the primary cause of cervical cancer. However, conventional PCR-based assays provide limited HPV genotyping, and cytology alone has low sensitivity for detecting subclinical infections. Comprehensive molecular approaches are needed to better characterize HPV genotypes and co-infections in community screening settings. METHODS: This study evaluated...
Topics
- Humans
- Female
- India
- High-Throughput Nucleotide Sequencing
- Papillomavirus Infections
- Genotype
- Adult
- Papillomaviridae
- Uterine Cervical Neoplasms
- Sexually Transmitted Diseases
