Article
Is ER-positive breast cancer a shield against myocardial infarction and its complications? A Mendelian randomization approach.
BMC cardiovascular disorders - 6 Jan 2026
Zhao Zehao, Cao Binbin, Li Jiahui, Chen Xiaomin
Abstract excerpt
BACKGROUND: Estrogen receptor-positive breast cancer (ER + BC) is the most prevalent subtype of breast cancer. However, the causal relationship between ER + BC and myocardial infarction complications remains unclear. While observational studies suggest a potential association between ER + BC and cardiovascular events, existing evidence does not provide sufficient causal inference. Mendelian randomization (MR)...
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