Article
The Health for Life in Singapore (HELIOS) Study: delivering precision medicine research for Asian populations.
Nature communications - 30 Dec 2025
Wang Xiaoyan, Mina Theresia, Sadhu Nilanjana, Jain Pritesh R, Ng Hong Kiat, Low Dorrain Yanwen, Tay Darwin, Tong Terry Yoke Yin, Choo Wee-Lin, Lim Liming, Kerk Swat Kim, Low Guo Liang, Lam Benjamin Chih Chiang, Dalan Rinkoo, Wanseicheong Gervais, Yew Yik Weng, van Dam Rob M, Leow Ee-J, Brage Soren, Michelotti Gregory A, Wong Kari E, Sheridan Patricia A, Low Pin Yan, Yeo Zhen Xuan, Bertin Nicolas, Bellis Claire, Hebrard Maxime, Goy Pierre-Alexis Vincent, Tsilidis Kostas, Sanikini Harinakshi, Guan Xue Li, Lim Tock Han, Lee Lionel, Best James D, Tan Patrick, Elliott Paul, Lee Eng Sing, Lee Jimmy, Ngeow Joanne, Riboli Elio, Lam Max, Loh Marie, Chambers John C
Abstract excerpt
Asian people are under-represented in population-based, clinical, and genomic research. To address this gap, we have initiated the Health for Life in Singapore (HELIOS) longitudinal cohort study, comprising comprehensive behavioural, phenotypic, and genomic measurements from 10,004 Asian men and women of Chinese, Indian or Malay background. Phenotyping has been carried out using validated approaches, that are...
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