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Article

MASLD versus MAFLD in lean steatotic liver disease: diagnostic overlap, inclusivity, and the metabolically healthy lean phenotype.

Clinical and experimental medicine - 23 Dec 2025

Elsabaawy Maha, Demerdash Heba, Ragab Amr, Naguib Madiha

Abstract excerpt

Lean non-alcoholic fatty liver disease (NAFLD) presents a unique clinical phenotype increasingly recognized within the evolving nomenclature of metabolic dysfunction–associated fatty liver disease (MAFLD) and metabolic dysfunction–associated steatotic liver disease (MASLD). This study evaluated the diagnostic applicability of both frameworks in lean Egyptian patients and explored their capacity to encompass...

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PMID: 41437157
DOI: 10.1007/s10238-025-01983-7
PMCID: PMC12769525

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