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Article

Unraveling the genetic association between autoimmune thyroid diseases and idiopathic inflammatory myopathies in the European population.

Medicine - 19 Dec 2025

Chang Le, Sun Zhen, Zeng Shiyong, Dong Xuefeng, Cai Zhenyu

Abstract excerpt

While clinical observations suggest potential links between thyroid autoimmunity disorders (specifically Hashimoto thyroiditis and Graves' disease) and idiopathic inflammatory myopathies (notably dermatomyositis and polymyositis), the underlying causative mechanisms remain incompletely understood. We implemented a Mendelian randomization approach to elucidate potential causal pathways through which thyroid...

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Identifiers

PMID: 41430975
DOI: 10.1097/MD.0000000000046670
PMCID: PMC12727279

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