A novel Pyrococcus furiosus argonaute-based method for rapid and sensitive detection of Mycoplasma pneumoniae and a macrolide-resistance-related mutation.

Abstract excerpt

Mycoplasma pneumoniae (MP) is a major cause of acute respiratory diseases. While macrolide resistance in MP has been recognized for decades, the recent surge in its prevalence has emerged as a growing clinical and public health concern. Rapid, sensitive, and specific detection of MP and macrolide-resistant Mycoplasma pneumoniae (MRMP) are crucial for preventing the spread of the disease. By leveraging the precise...

Topics

• Mycoplasma pneumoniae
• Drug Resistance, Bacterial
• Pyrococcus furiosus
• Sensitivity and Specificity
• Humans