Article
HIV-1 virologic failure in the RESINA cohort: lessons from two decades of real-world data.
Infection - 1 Apr 2026
Gliga Smaranda, Böhm Micha, Lübke Nadine, Killer Alexander, Hüttig Falk, Haberl Lila, Timm Jörg, Müller Claudia, Heger Eva, Büch Joachim, Fätkenheuer Gerd, Lehmann Clara, Oette Mark, Hower Martin, Knechten Heribert, Schübel Niels, Esser Stefan, Schneeweiß Stephan, Qurishi Nazifa, Römer Katja, Rockstroh Jürgen K, Kaiser Rolf, Luedde Tom, Jensen Björn-Erik Ole
Abstract excerpt
PURPOSE: To quantify virologic failure (VF), identify predictors, characterize resistance patterns at failure, and evaluate time to resuppression in the RESINA cohort. METHODS: ART-naïve adults initiating ART in 2001-2024 were followed. VF was defined as at least one HIV-1 RNA > 200 copies/mL after suppression or ≥ 0.5-log₁₀ rebound. Participants were grouped by treatment era (2001-2007, 2008-2013, ≥ 2014),...
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