Article
Telomere-to-telomere genome assembly of a male pig provides insight into population structure and selection for body stature.
Nature genetics - 1 Jan 2026
Luo Ya-Biao, Huang Ning, Zha Cheng-Wan, Yang Li-Xian, Xue Peng-Xiang, Xu Qiao, Yang Xiao-Yang, Zhang Long-Miao, Wang Yu-Bei, Chao Zhe, Sun Rui-Ping, Wang Feng, Jia Shan-Gang, Fang Mei-Ying
Abstract excerpt
A complete telomere-to-telomere (T2T) genome is essential for advancing pig genomic research. Here we assembled a pig T2T gap-free genome T2T-pig1.0 (2.63 Gb) for a boar in Wuzhishan, China, covering all 20 chromosomes. T2T-pig1.0 with an accuracy of >99.999% uncovers 194.42 Mb of previously unresolved regions (PURs), and 1,189 new genes are added to the current reference genome Sscrofa11.1. We annotated 111...
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