Article
Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits.
Nature communications - 20 Nov 2024
Wu Hui, Luo Ling-Yun, Zhang Ya-Hui, Zhang Chong-Yan, Huang Jia-Hui, Mo Dong-Xin, Zhao Li-Ming, Wang Zhi-Xin, Wang Yi-Chuan, He-Hua EEr, Bai Wen-Lin, Han Di, Dou Xing-Tang, Ren Yan-Ling, Dingkao Renqing, Chen Hai-Liang, Ye Yong, Du Hai-Dong, Zhao Zhan-Qiang, Wang Xi-Jun, Jia Shan-Gang, Liu Zhi-Hong, Li Meng-Hua
Abstract excerpt
A complete goat (Capra hircus) reference genome enhances analyses of genetic variation, thus providing insights into domestication and selection in goats and related species. Here, we assemble a telomere-to-telomere (T2T) gap-free genome (2.86 Gb) from a cashmere goat (T2T-goat1.0), including a Y chromosome of 20.96 Mb. With a base accuracy of >99.999%, T2T-goat1.0 corrects numerous genome-wide structural and...
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