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Article

Improving Efficiency in Dutch Cervical Screening by Genotyping: An Analysis of Real World Program Data.

Journal of medical virology - 1 Dec 2025

Olthof Ellen M G, van den Brule Adriaan J C, Melchers Willem J G, Berkhof Johannes, de Kok Inge M C M

Abstract excerpt

High-risk human papillomavirus (hrHPV)-genotype specific risk stratification may improve cervical screening efficiency. This study evaluates the risks of cervical intraepithelial neoplasia (CIN), cancer and unnecessary referrals by hrHPV-genotype in cytology-positive (ASCUS+) women, using data from the Dutch population-based cervical screening program. Data from hrHPV+/ASCUS+ women screened between January 2017...

Topics

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Early Detection of Cancer
Human papillomavirus 16
Human papillomavirus 18
Mass Screening
Netherlands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papillomaviridae

Uterine Cervical Dysplasia

Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 41367324
DOI: 10.1002/jmv.70745
PMCID: PMC12690436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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