Article
Distribution of Human Papillomavirus Genotypes in Real-World Cervical Self-Collected Scrapings From the Dutch Cervical Cancer Screening Program.
Journal of medical virology - 1 Jul 2025
Castañeda Kelly Melisa, de Waard Jolien, Slagter-Menkema Lorian, Mastik Mirjam, Vuijk Floris Adriaan, Bekkers Rudolf Lambertus Maria, de Bock Geertruida Hendrika, Wisman Gijsbertha Barendina Alida, Schuuring Ed
Abstract excerpt
High-risk HPV (hrHPV) is the necessary cause of cervical cancer with HPV16/18 accounting for around 70% of the cases worldwide, while other non-HPV16/18 hrHPV genotypes prevail in ~95% of high-grade lesions. Understanding regional genotype distribution of hrHPV types not covered by the nonavalent vaccine is crucial for evaluating vaccine effectiveness and enhancing population-based screening (PBS). The objective...
Read the complete abstract on PubMedTopics
- Humans
- Female
- Genotype
- Netherlands
- Papillomavirus Infections
