Article
Improving cervical screening risk stratification through extended human papillomavirus genotyping and age-specific data.
European journal of public health - 4 Aug 2026
Leino Aarno, Numminen Eero, Fonagy Veronika, Paloniemi Minna, Seiskari Tapio, Kholová Ivana, Kares Saara, Louvanto Karolina
Abstract excerpt
High-risk human papillomavirus (HR-HPV) screening effectively reduces cervical cancer incidence, but limited specificity leads to excessive colposcopy referrals. Extended HR-HPV genotyping improves triage by accounting for genotype-specific oncogenic risks, offering a more precise framework for patient management than traditional pooled testing. This study analysed real-world screening data from a Finnish cohort...
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