Article
From misclassified AIP variant to carney complex: a case report and retrospective evaluation of PRKAR1A in pituitary tumor predisposition.
Pituitary - 9 Dec 2025
Piazzola Cécilia, Le Collen Lauriane, Charnay Théo, Decoudier Bénédicte, Albarel Frédérique, Macagno Nicolas, Castinetti Frédéric, Barlier Anne, Delemer Brigitte, Romanet Pauline, Auragen Consortium
Abstract excerpt
CONTEXT: Carney Complex (CNC) is a rare multiple endocrine neoplasia syndrome, due to PRKAR1A mutation, that causes GH-secreting pituitary adenomas (PA) in 10% of patients. PRKAR1A is not currently analyzed in patients with isolated sporadic or familial PA, in contrast to MEN1 or AIP. OBJECTIVE: We report the case of a young man diagnosed with a PA at age 21 during melanoma follow-up, with a family history of PA....
Topics
Join the communities discussing this publication.