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Article

A novel duplication mutation in the MYO7A gene associated with autosomal recessive hearing loss in a Chinese family.

Genes & genomics - 1 Feb 2026

Li Jie, Yang Shengmei, Xiang Mina, An Qingling, Wu Yuannan, Quan Qingli, Jiang Haiou

Abstract excerpt

BACKGROUND: Hearing loss (HL) is one of the most common sensory defects with genetic and environmental etiologies, which is classified into syndromic and non-syndromic hearing loss (NSHL). Variants in MYO7A have been found to result in non-syndromic hearing loss (DFNB2, DFNA11) and Usher Syndrome type 1B (USH1B). However, only a small number of variants result in DFNB2. OBJECTIVE: To explore the pathogenic...

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Source

Identifiers

PMID: 41359246
DOI: 10.1007/s13258-025-01716-w

Genes

MYO7A

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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