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Article

Hiding in plain sight: Genomic and phenotypic characterization of mosquito-borne Bussuquara virus.

PLoS neglected tropical diseases - 1 Dec 2025

Steck Madeline R, Banho Cecília A, Popov Vsevolod L, Hao Haiping, Hanley Kathryn A, Nogueira Mauricio L, Vasilakis Nikos

Abstract excerpt

Bussuquara virus (BSQV), an orthoflavivirus discovered in Brazil in 1956, has been detected throughout the Americas in diverse mosquito and vertebrate species, including humans. Critical gaps in BSQV knowledge include its capacity for urban transmission and clinical pathogenesis outcomes, with insufficient historical experimentation to draw genomic or phenotypic comparisons to related orthoflavivirus species. The...

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PMID: 41348856
DOI: 10.1371/journal.pntd.0013774
PMCID: PMC12680234

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C6

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