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Article

Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family.

Proceedings of the National Academy of Sciences of the United States of America - 16 Jun 2015

Marklewitz Marco, Zirkel Florian, Kurth Andreas, Drosten Christian, Junglen Sandra

Abstract excerpt

The evolutionary origins of arboviruses are unknown because their typical dual host tropism is paraphyletic within viral families. Here we studied one of the most diversified and medically relevant RNA virus families, the Bunyaviridae, in which four of five established genera are transmitted by arthropods. We define two cardinally novel bunyavirus groups based on live isolation of 26 viral strains from mosquitoes...

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PMID: 26038576
DOI: 10.1073/pnas.1502036112
PMCID: PMC4475995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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