Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence-Associated Properties.

Abstract excerpt

Acinetobacter baumannii is a multi-drug resistant Gram-negative coccobacillus. It is responsible for high mortality among patients in the intensive care unit. Reported A. baumannii virulence factors include the thioredoxin system which plays a critical role in gene regulation and protein reduction. The Type IV pilus (T4P) is a well-known bacterial virulence factor that is associated with adhesion and molecular...

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