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Article

High connectivity and low differentiation of Plasmodium falciparum parasite populations in a setting with high seasonal migration.

Scientific reports - 26 Nov 2025

Esayas Endashaw, Louie William, Routledge Isobel, Murphy Maxwell, Demeke Nigatu Negash, De Amaral Faith, Aranda-Díaz Andrés, Greenhouse Bryan, Kassa Fikregabrail Aberra, Nigusse Tedros, Assefa Muluken, Ashine Temesgen, Getachew Asefaw, Ntuku Henry, Golassa Lemu, Gadisa Endalamaw, Bennett Adam, Smith Jennifer L

Abstract excerpt

Seasonal movement of less-immune people from low- to high- transmission regions increase malaria risk and may introduce parasite strains to both areas. This study examined Plasmodium falciparum genetic diversity and connectivity between low-transmission highlands and endemic lowlands in Ethiopia to assess the contribution of seasonal agricultural migration in sustaining transmission. P. falciparum qPCR-positive...

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Identifiers

PMID: 41298827
DOI: 10.1038/s41598-025-29271-0
PMCID: PMC12749964

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