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Article

Patient-derived epithelial cell organoids mimic the phenotypic complexity of endometriosis subtypes.

Human reproduction (Oxford, England) - 1 Feb 2026

Gunther K, Liu D, Cortesi M, Powell E, Nesbitt-Hawes E, Abbott J A, Ford C E

Abstract excerpt

STUDY QUESTION: Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology? SUMMARY ANSWER: Endometriosis organoids can be established across all major surgical phenotypes with variable efficiency, and hormonal treatment at the time of biospecimen collection...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41298340
DOI: 10.1093/humrep/deaf230
PMCID: PMC12864149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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