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Article

Comparative Proteomic Profiling of Adrenocortical Neoplasia Using Mass Spectrometry.

Journal of proteome research - 5 Dec 2025

Kremer Jean Lucas, Ortega Henrique Sanchez, Siqueira-Souza Talita, Angeli Claudia Blanes, Iwai Leo Kei, Lotfi Claudimara Ferini Pacicco

Abstract excerpt

Recent advances in high-throughput molecular analysis have significantly enhanced our understanding of the molecular mechanisms underlying adrenocortical diseases. To identify differences in protein signatures that may reveal insights into disease-specific pathogenesis, we used LC-MS/MS and bioinformatics to compare proteomic profiles of normal human adrenal (NHA) tissue, adrenocortical adenomas (ACA),...

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Identifiers

PMID: 41269005
DOI: 10.1021/acs.jproteome.5c00740
PMCID: PMC12687312

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