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Deciphering vancomycin resistance in Enterococcus faecium: gene distribution, sequence typing, and global phylogenetic analysis

15 Aug 2025

Abstract excerpt

Objective This study analyzes the global prevalence and distribution of vancomycin resistance genes (van) in Enterococcus faecium and examines the genetic relationship and epidemiological characteristics of strains carrying these genes. Method A total of 3,256 E. faecium genome sequences were downloaded, and 2,235 high-quality genomes were retained after quality filtering. The blastn tool was used to screen these...

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PMID: 40895472
DOI: 10.3389/fmicb.2025.1578903

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