Article
PMEL as a candidate gene for coat color differentiation in Sibu yaks: Genetic and functional insights.
Zoological research - 18 Nov 2025
Zhang Hao-Yuan, Xu Lu, Wang Jin-Huan, Ceccobelli Simone, Zhu Yong, Zhang Qiang, Zhang Cheng-Fu, Hu Peng-Fei, Liu Cheng-Li, Yang Bai-Gao, Ruan Peng-Cheng, Ren Tao, Cong He, Zeng Yan, Han Yan-Guo, Wang Shi-Zhi, Zhao Yong-Ju, Zhao Zhong-Quan, Huang Yong-Fu, Nie Wen-Hui, E Guang-Xin
Abstract excerpt
Coat color represents a key phenotypic trait in Sibu yak, exhibiting distinct black and brown phenotypes. To elucidate the genetic basis of the brown phenotype, genome-wide association studies and multi-omics analyses were integrated to identify loci and molecular pathways involved in pigmentation. In total, 11 single-nucleotide polymorphisms (SNPs) on chromosome (chr) 5 displayed genome-wide significance (...
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