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Article

Identifying a digital phenotype of allostatic load: association between allostatic load index score and wearable physiological response during military training.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2025

Feigel Evan D, Koltun Kristen J, Lovalekar Mita, Bird Matthew B, Kargl Christopher K, Forse Jennifer N, Martin Brian J, Nagle Elizabeth F, Steele Elizabeth J, Doyle Tim L A, Friedl Karl E, Nindl Bradley C

Abstract excerpt

Allostatic load, a maladaptive biological process wherein physiological stability ("allostasis") fails owing to chronic stress exposure, is traditionally measured by the allostatic load index (ALI). Whether ALI is associated with wearable-assessed physiological responses remains unknown. We aimed to determine the association between ALI and wearable-assessed physiological responses during a 10-wk military...

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PMID: 41223069
DOI: 10.1152/ajpregu.00216.2025

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