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Habitual napping and cancer incidence: a prospective study from the UK Biobank with metabolomic mediation analysis.

Sleep - 10 Feb 2026

He Juan, Wu Xinyi, Ye Wenjun, Li Feng, Feng Yi, Zheng Xiangyuan, Wu Yuling, Cai Jingjia, Wei Yihai, Diao Jingwen, Liang Jie, Wang Zixun, Xian Chengfu, Bi Xin, He Jianxing, Cheng Bo, Liang Wenhua

Abstract excerpt

STUDY OBJECTIVES: This study aims to investigate the association between daytime napping frequency and cancer incidence and elucidate the underlying biological mechanisms. METHODS: Using data from the UK Biobank, Cox regression was employed to assess the association between self-reported daytime napping frequency and risks for overall and site-specific cancers. A polygenic risk score (PRS) was conducted to assess...

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PMID: 41206730
DOI: 10.1093/sleep/zsaf331

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