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Genetic Characterization and Evidence of Capsid Epitope Variation in Porcine Circovirus Type 3 Strains from Vietnamese Swine with Reproductive Disorders.

Current microbiology - 8 Nov 2025

Pham Long Ngoc Huynh, Dinh Phat Xuan, Ngo Tram Ngoc Thi, Le Ha Thu Thi, Do Duy Tien

Abstract excerpt

This study investigated the presence and genetic diversity of porcine circovirus type 3 (PCV3) in Vietnam. Fifteen samples from sows with reproductive disorders across five provinces were screened by qPCR; those with Ct-values < 25 underwent sequencing. Whole-genome analysis revealed multiple polymorphisms, including a notable A24L substitution in the ORF2 Cap protein. Phylogenetic results showed 13 strains...

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PMID: 41204966
DOI: 10.1007/s00284-025-04600-8

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