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Association of MHC class II β domain polymorphism in channel catfish (Ictalurus punctatus) with natural infection by Ligictaluridus floridanus.

Parasitology research - 29 Oct 2025

Roldán Guadalupe Moncerrat González, Bracamonte Gaspar Manuel Parra, González Flaviano Benavides, Alfaro Isidro Otoniel Montelongo, Di Carlo Quiroz Velásquez Jesús, De La Rosa-Reyna Xochitl F

Abstract excerpt

The major histocompatibility complex (MHC) class II β genes are highly polymorphic and trigger the adaptive immune response in fish against parasitic infections. In channel catfish, exon 2 of the HLA (human leukocyte antigens) and H-2 genes encodes the MHC class II β domain. HLA and H-2 have not been documented in channel catfish populations or associated with parasite infections. We used Ligictaluridus...

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Topics

Animals
Ictaluridae
Fish Diseases
Polymorphism, Single Nucleotide
Histocompatibility Antigens Class II

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Identifiers

PMID: 41152642
DOI: 10.1007/s00436-025-08575-0
PMCID: PMC12568915

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