Article
Perianal Intestinal-Type Paget Disease With and Without Invasion, Unassociated With Internal Malignancy: A Distinct Form of Primary Perianal Adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2026
Bahceci Dorukhan, Saoud Carla, Isidro Raymond A, Caires Diogo, Moher Conrad James, Urganci Nil, Pulitzer Melissa, Garcia-Aguilar Julio, Weiser Martin R, Vakiani Efsevia, Srivastava Amitabh, Shia Jinru
Abstract excerpt
Primary perianal adenocarcinoma of intestinal type (PPAI) has been described in recent literature and proposed as a subtype of extramucosal anal adenocarcinoma. Whether this represents a unique entity remains to be elucidated. Herein, we analyzed the clinicopathologic and genomic features of 14 cases of PPAI. Fourteen patients, predominantly older adults with a median age of 73 years (range, 50-85), with a slight...
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