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Article

Membrane frizzled-related protein: a comprehensive analysis of genetic characteristics, phenotypic manifestations and impact on retinal microvasculature.

Ophthalmic genetics - 1 Dec 2025

Simsek Metehan, Ozbek Merve, Ayata Selim, Yarali Oguzhan, Yarali Yusuf Alperen, Artunay Ozgur

Abstract excerpt

PURPOSE: To assess the ocular characteristics, retinal microvasculature, and long-term outcomes of patients with nanophthalmos associated with mutations in the membrane frizzled-related protein (MFRP) gene, and to compare these findings with those observed in nanophthalmos cases without MFRP gene mutations. METHODS: In this retrospective cohort study, patients with MFRP-associated nanophthalmos and those with...

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Identifiers

PMID: 41039698
DOI: 10.1080/13816810.2025.2566428

Genes

MFRP

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